Lost Vape Therion DNA75C review by VapeMaster

Review Date: 

Lost Vape Therion DNA75C

From Lost Vape, the Therion dual 18650 box mod. The Therion features the DNA75C chipset from Evolv and features a variety of changes over the initial DNA75 which include a full colour screen, an extra navigation button and dizzying amount of new EScribe information along with a theme generator for even more customisation!

The devices offers up to 75 Watts of power and can be used in either Variable Wattage or Temperature Control Mode with full support for all major wire types. It all sounds very impressive but will this device surpass the previous Therion model? We shall see!

Lost Vape Therion DNA75C features

  • Die Cast Zinc Alloy Construction.
  • Requires 2x Dual 18650 High-Amp Batteries (Not Included).
  • Wattage Output Range: 1-75W.
  • Voltage Output Range: 0.6-9V.
  • Minimum Kanthal Resistance: 0.25ohm.
  • Minimum Temperature Control Mode Resistance: 0.15ohm.
  • Temperature Range: 200-600F.
  • Supports Ni200 Nickel, Titanium, NiFE30, Stainless Steel 316, Stainless Steel 430 and Nichrome.
  • Intuitive OLED Display.
  • Genuine Leather Magnetic Battery Door.
  • Carbon Fibre Inlay Panels.
  • Three Adjustment Button Operation.
  • Patented Evolv DNA75C Chipset.
  • Upgradeable Escribe Software - Theme Generator.
  • 85% Output Efficiency.
  • Cell-by-Cell Monitoring.
  • Cell Balancer.
  • Atomizer Protection.
  • Low Resistance Protection.
  • Short Circuit Protection.
  • Overheat Protection.
  • Low Voltage Step-Down Protection.
  • Micro USB Port - Firmware Upgrades.
  • Stainless Steel 510 Threaded Connector.
  • Spring-Loaded Nickel Plated Brass 510 Pin.

What’s in the box?

  • 1x Therion DNA75C.
  • 1x Micro USB Cable.
  • User Manual.
  • Warranty Card.

Lost Vape Therion DNA75C styling and build quality

In terms of styling the Lost Vape Therion DNA75C is almost identical to the Therion 166 apart from a few small changes which include an additional button and a full colour screen. Another noticeable change is that this device only offers up to 75 Watts of power. The main material used in its construction is die cast zinc alloy so it is fairly light but feels much more solid when fitted with batteries. It is very well made, nicely balanced and feels extremely comfortable to hold!

You can purchase the Therion in either a silver or black finish. Unlike the initial Therion’s which had ebony wood inlay accents (before switching to carbon fibre when the Black Edition was released) the Therion DNA 75C also features carbon fibre which looks very complimentary and stylish.

At the top of the device you will find the Stainless Steel 510 connector which has superb and highly durable threading. The connector is secured to the chassis with three Stainless Steel screws and it is completely flush with the top of the device. The 510 pin is spring-loaded and is made from Silver Plated Nickel. I had absolutely no problems getting any of my atomizers to sit flush. The overall size of the connector is about 25mm in diameter so any atomizers up that size will look great on the Therion! The Micro USB port is located on the bottom front of the device and can be used for either charging or connecting to your computer to make use of EScribe software and firmware updates.

The Therion DNA75C has four buttons which feel durable, are highly responsive and have a lovely feel to them which means only a light touch is needed. As you might expect given the quality of this device’s construction there is absolutely no rattle at all.

The full colour screen is bigger than the one on the 166 and displays the information vertically rather than horizontally. It is nicely recessed and very bright. The new menu layout takes a little getting used to but the information is nicely presented. Everything is now context sensitive so the amount of information displayed is limited to the mode which you are currently in which keeps everything clutter free. All of the typical information can be displayed such as Wattage, Voltage and Resistance as well as Amps, Battery Life and Temperature (when it that mode). In addition the display also shows when the Resistance Lock is enabled and if you don’t like the layout you can personalise exactly what is displayed via use of the EScribe software but you will require access to a computer.

One concern I have is the battery compartment since the batteries feel like a much tighter fit than the Therion 166, so do be careful not to damage the wraps. A noticeable change is that the batteries are now fitted in parallel unlike the 166 where they are fitted in series. The battery orientation is clearly marked and there is a ribbon to assist with battery removal. The battery contacts are 24K Gold-plated for excellent conductivity. The tolerance on the battery door is a massive improvement over the Therion 166 and there is absolutely no wobble whereas the 166 doors always have a bit of play. Just like the Therion 166 the magnetic clip style battery door has a beautiful real leather wrap which is available in a variety of styles and colours. The device I received came with a Purple Ostrich cover but I seriously like the Africa, Bush Viper and Grey Rat covers which are available! Given that you can buy individual battery doors the device offers a nice degree of personalisation!

Just like the Therion 166 this device has absolutely no venting whatsoever. 

Ease of use

Now initially I wasn’t a huge fan of the new menu system but after using the device for a day it really started to grow on me. It is very straightforward to understand but it might feel a little weird to begin with for anyone who is used to existing DNA devices. Once I got used to the new system I really started to appreciate it and it works a great deal like a remote control with the up and down buttons moving between highlighted options and confirming with the middle button.

Everything in the menu is context sensitive and easily accessed. To cover every option on this device would make this section longer than the entire review but rest assured the manual does a thorough job of explaining everything.


The one thing I always notice with any DNA device is how the vape is slightly smoother than other devices and that is very true of the Therion DNA75C. When using this mod in Wattage Mode it works consistently well and delivers an excellent vape!

When using Temperature Control Mode the device has the same superb performance as the Therion 166, with no Resistance jumping or fluctuation. A number of pre-sets are included for the most common wire types so you will not need to mess around with EScribe unless you really want to. From a performance point of view I was highly impressed with this device but it does seem to drain the batteries much faster than my 166.

As I mentioned earlier this device has no obvious venting and it does get quite warm on occasion, especially around the screen and the top of the device so you will certainly notice it if you chain vape. I feel that the larger screen is contributing to the increased heat and perhaps the tighter battery cover is another reason for it. It shouldn't be a problem but I do want you to be fully aware of it.


While this device has the same excellent build quality as the existing Therion 166 in some respects the battery door on the DNA75C is a definite improvement and I certainly loved the new screen once I got used to it.

One issue for existing Therion users is that this device only offers up to 75 Watts of power yet it is sold at the same premium price as the 166 due to this featuring the latest Evolv chipset. Now the price is understandable and fair enough providing you are someone who will make full use of the chip and dabble heavily in EScribe. Another concern is that my batteries do drain faster in this device compared to my Therion 166 but perhaps this is due to the new colour screen.

In terms of general performance the device works flawlessly in both Variable Wattage and Temperature Control which is something you would expect from the latest Evolv chipset so you are certainly getting value for your money. Another consideration is that tech-minded users will appreciate the increased customization in EScribe.

Overall this is a great device - and bear in mind that the firmware update that is due soon will bring the new replay feature to this device, so if you can hunt one down they are well worth a try.