I have done previously with the harder bottles (pico squeeze) and they were fine, but never tried the soft silicone ones as I never needed to but I don't see why not!
No issues using US but it wont get rid of odours.
Let me know how you get on, I had no luck through 5 cycles but didn't try Milton.
I made the mistake of trying to boil wash them, they hardened.
The only fix I found was buying new ones
Milton, unflavoured denture tablets or bicarb best way to shift odours. Bicarb worked for me on heisenberg type juice so tobacco should be a walk in the park.